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Examining the "worried well" phenomenon: insights from Italy’s AIDS and STIs Helpline

Authors

Abstract

Background. The fear of having contracted HIV or another sexually transmitted infection (STI), even in the absence of significant risk factors, is a globally observed phenomenon across diverse cultural, social, and healthcare settings. Helplines serve as a valuable observatory for this pattern, often described as “worried well” (WW). This study investigates the WW phenomenon with the objective of assessing whether the COVID-19 pandemic has acted as a compounding factor in its intensification.
Methods. AIDS and STIs Helpline of the Italian National Institute of Health (Istituto Superiore di Sanità, ISS) extracted data from a structured database and analyzed patterns related to callers’ concerns.
Results. Between 2018 and 2023, 4,703 calls were analysed, showing how WWs represent 8.1% of all users and questions asked by WWs accounted for 7.8% of the total number of questions received by the AIDS and STIs Helpline.
Conclusions. While the COVID-19 pandemic may have contributed to an intensification of the WW phenomenon, its origins are more deeply rooted in factors such as psychological distress and limited health literacy.

INTRODUCTION

Over the years, several health services specializing in sexually transmitted infections have documented and examined the phenomenon commonly referred to in the literature as the “worried well” (WW).

Worried well individuals are those who experience excessive distress or anxiety concerning their health and who engage in frequent, often repetitive, health-related searches on the Internet, which tend to exacerbate rather than alleviate their concerns. In the context of HIV, AIDS, and other sexually transmitted infections (STIs), this phenomenon is particularly salient, as it often manifests as a pronounced form of health anxiety that can significantly impair daily functioning, occupational performance, and overall psychosocial well-being [1]. In the scientific literature, these subjects are often referred to as “worried well people” or as subjects suffering from venerophobia [2-5].

The terminology may imply the absence of pathological conditions; however, the state referred to as “worried well” can be profoundly debilitating for the individual.

It is inappropriate to dismiss anxiety associated with such conditions as clinically irrelevant solely due to the absence of identifiable risk factors, as this anxiety may in fact reflect an underlying pathological condition warranting clinical attention [6].

Evidence of this phenomenon has been documented by the Dutch AIDS Information Helpline, where individuals classified as “worried well” frequently utilize telephone-based services related to sexually transmitted infections. Notably, in approximately half of the calls received, users assessed their own risk profile as greater than that estimated by the operator, with the most commonly sought form of assistance being reassurance regarding the absence of risk. [7].

Based on the experience of the AIDS and STIs Helpline of the Italian National Institute of Health (Istituto Superiore di Sanità, ISS), these users repeatedly and insistently return to the same questions and/or specific topics, despite having already received comprehensive information and guidance during their initial call. Some of these individuals report no actual risk behaviors or, in cases where a potential risk factor is present, express fear of undergoing diagnostic testing or skepticism regarding the validity of previous negative test results.

These users require a significant investment of time and resources from the helpline professionals, who must therefore be adequately trained to implement telephone interventions grounded in specific counselling competencies.

Although the number of studies published on this phenomenon remains limited, it is nonetheless evident that the issue has assumed global dimensions, impacting both clinical and organizational aspects within counselling and screening services for infectious diseases, as well as in the fields of psychiatry and behavioral disorders. Moreover, it is important to highlight that this behavior can be observed across a wide range of contexts worldwide, varying significantly in terms of cultural, economic, and healthcare management systems, and it cannot be considered confined to specific health, socio-economic, or environmental conditions.

This article presents the findings of a study conducted over three consecutive two-year periods (2018-2019, 2020-2021, 2022-2023), aimed at determining whether the COVID-19 pandemic has exacerbated the phenomenon of pathological fear of STIs. This was assessed by comparing data across the three periods, defined respectively as pre-pandemic, pandemic, and post-pandemic. The study also seeks to identify the socio-demographic and behavioral characteristics, as well as the underlying motivations, of individuals who repeatedly contacted the AIDS and STIs Helpline of the Istituto Superiore di Sanità.

METHODS

The AIDS and Sexually Transmitted Infections Helpline (800 861061) – operated by the Istituto Superiore di Sanità and active since 1987 – delivers effective interventions aimed at the primary and secondary prevention of HIV, AIDS, and other sexually transmitted infections (STIs).

The service is situated within the Communication Division of the Operational Unit for Psycho-Socio-Behavioral Research, Communication, and Training (Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione - UO RCF) of the Department of Infectious Diseases (Dipartimento Malattie Infettive, DMI).

Case definition: the Authors analyzed calls made by individuals who placed two or more calls to the TV AIDS and STIs Helpline within a 30-day period, exhibiting an unfounded fear of HIV and other STIs throughout the counseling intervention. Despite not presenting any significant risk factors for HIV or STIs in general, these individuals nevertheless fear being infected to the extent that they limit their social, relational, and sexual lives.

The telephone intervention is structured around the core competencies of counselling and is organized into phases according to the Communicative-Relational Operating Model. A dedicated data-entry interface and ad hoc software enable the storage and analysis of data collected during counselling activities.

Researchers from the UO RCF have developed the Communicative-Relational Operating Model (MO), based on the fundamental skills of counselling. This model facilitates the development of effective telephone communication with users, allowing for personalized responses through the integration of technical-scientific knowledge and relational-communicative competencies [8].

Data collection is carried out in a structured manner using a database specifically designed to ensure the security of large-scale information, whether stored on the institution’s internal servers or in the cloud. In particular, cloud storage is configured to preserve data confidentiality, with data managed through a standardized data collection form.

Instruments: for each call, data are collected across various sections, including: frequency of calls per user (based on self-reported information), age, gender, personal characteristics either self-reported by the user or inferred by the operator from the context of the call, type of situation (real or hypothetical), topics of the questions – specifically modes of transmission, symptoms, questions about testing, emotional state, misinformation, and access to Pre-exposure prophylaxis (PrEP) and Post-exposure prophylaxis (PEP). A descriptive analysis of the aggregate data collected during the telephone interventions was performed using Access 365 software.

Data analysis/Results

The general data regarding calls made by WW users in the study period extending from 2018 to 2023 (4,703 out of a number of questions equal to 16,401), compared with the overall number of calls received by the service in the same period of time (53,068 out of a number of questions equal to 192,667) show how calls from WW represent 8.87%, and questions asked by WW users accounted for 8.51% of the total number of questions received by the AIDS and STIs Helpline (Table 1).

Sample characteristics

The data relating to age highlight that the population represented by the WW has a higher median age (41 years – IQR 33-47) compared to the general user population (35 years – IQR 28-42).

Analyzing the distribution of calls between the two genders, it emerges that women represent a significantly higher percentage among the WW (19.3%) compared to the percentage of women in the general user population (15.0%).

In 24.8% of calls from WW, users declare having already carried out more than one HIV test, compared to a percentage of 46.6% in the general user population. Just 12.2% of WW declare that they have never had an HIV test compared to a percentage of 38.3% in the calls of the general population.

Data highlight that calls made by WW users show the absence of risk factors in a percentage of 96.3%, whereas in calls from the general users population such percentage amounts to 76.9%.

The total number of questions formulated by the WW amounted to 16,401 compared to a number of 192,667 in the general user population. From the analysis of the requests formulated by the two population groups, we can observe that the incidence of questions relating to the infectious potential and resistance of pathogens (17.1% in the WW group and only 5.4% in the general user population) shows significant statistical differences.

The differences found in the calls made by the two compared groups of users were statistically significant (p value<0.001) (Table 1).

The gender analysis carried out on calls by WW highlights how in 27.3% of cases the questions related to misinformation are asked by female users, while the requests on this topic by men represent 25%. As regards questions relating to the contagiousness and survival of pathogens, 18% of the requests were made by female users while 16.9% were made by male users. As for questions on the ways of transmission, male users are prevalent (18%) compared to female users, who represent 15% of calls. With regards to psycho-social aspects, female users return to being prevalent over male users (16.3% vs 15.8%). Finally, 17.1% of women and 15.6% of men ask for specific information on the diagnostic test (Figure 1).

RESULTS

Comparison between the numbers relating to calls from WW users in the three two-year periods of study

Analyzing the data relating exclusively to calls from WW users in the three periods under study, it emerges that there is a progressive increase in the median age (from 40 in the first two-year period to 42 in the third). This increase in age is particularly accentuated in the over 50 age group, raising from 15.0% in the first two years to 19.3% in the second and reaching 27.1% in the third two years period (Table 2).

In terms of geographical origin, there was an increase in calls from WW users declaring to live in the southern regions throughout the second and third two-year periods (35.1% in the second two-year period, 31.5% in the third, compared to 27.8% in the first).

The distribution of calls by users’ gender shows an increase in calls from male users between the first and third two-year period (from 80.0% to 84.0%). As regards calls from women, the increase is significant in the second two-year period (21.0% compared to of 20.0% in the first), decreasing significantly in the third (16.0%).

The trend in the frequency of calls from WW in the three periods highlights a significant increase in the number of calls from individuals who repeatedly contact the Helpline (even more than 15 times), going from 34.7% in the first two years to 57.6% in the second, decreasing to 51.7% in the third.

The data relating to the number of HIV tests carried out shows that the percentage of calls from WW users who declare that they have never carried out the test drops from 13.9% in the first two years to 7.3% in the last, while the calls from WW who have carried out multiple tests pass from 22.9% in the first two years to 29.4% in the last.

On the other hand, there were no significant variations in the type of questions asked by WW users, with the exception of a modest increase, during the three two-year periods, in the number of questions relating to psycho-social aspects.

The data trends observed across the three analyzed periods suggest a likely significant association between the environmental conditions induced by the pandemic and the incidence of Helpline calls from users who may be classified as WW.

Over the course of the three two-year periods, the number of individuals contacting the AIDS and STIs Helpline due to an irrational fear of having contracted HIV, or of having been at risk of doing so, followed a trend that clearly highlights the complete absence of any actual risk factors in the majority of cases. Notably, there is a persistent subset of callers who, even after receiving scientifically accurate and up-to-date information about HIV transmission and the lack of any risky behavior, continue to seek further reassurance through repeated calls (Table 2).

DISCUSSION

The present study analyzes the characteristics of phone calls made by WW users across three two-year periods, highlighting the specific features of this group of calls and examining their quantitative and qualitative variations before, during, and after the COVID-19 pandemic.

The data show that the pandemic amplified the fears expressed by the study sample. The end of the pandemic only partially mitigated this effect, without returning to pre-pandemic levels.

Notably, the median age reported in calls from WW users is significantly higher than that reported in calls from non-WW users.

Moreover, only 3.7% of WW calls report the presence of one or more risk factors, compared to 23.1% of calls from the non-WW user population. This suggests that the perception of infectious risk within the study sample is significantly more influenced by emotional factors and a distorted perception of reality than in calls made by non-WW individuals. This interpretation is supported by the fact that in 33.9% of calls from WW, users reported having undergone HIV testing despite the absence of identifiable risk factors.

These findings highlight how the use of diagnostic services without actual exposure to risk is highly prevalent within the analyzed sample, where both misinformation and emotional responses play a markedly disruptive role.

Misinformation was identified in 25.5% of calls from WW users, a significantly higher proportion compared to only 7.6% in calls from non-WW users. This finding is particularly noteworthy, as calls from WW clearly indicate a tendency to engage in obsessive online searches for detailed information about risk factors. However, this behavior does not appear to result in a genuine increase in awareness regarding the transmission and prevention of STIs.

It thus appears that the combination of limited health literacy – commonly observed in calls from both WW and non-WW users – and the distinctive emotional and personality traits characteristic of WW users renders this group of Helpline callers clearly identifiable. These observations are consistent with findings from multiple studies conducted over time on the WW phenomenon in various global contexts.

A number of observational studies, conducted in India and Nepal between 2017 and 2020, within clinical settings dedicated to dermatology and venereology [2-5], describe the characteristic traits of venerophobia, consisting of an irrational fear of having contracted a sexually transmitted disease (STD) following single or repeated sexual intercourse. This condition can have serious consequences on the good health and well-being of those affected.

The phenomenon has been observed mainly among young males and is often a consequence of sexual relationships with sex workers or of extramarital sexual relationships that are associated with feelings of guilt and shame.

In such cases, the altered emotional state and persistent anxiety are not necessarily associated with a complete absence of risk factors. However, a defining characteristic of these individuals is a persistent tendency to undergo repeated diagnostic testing for sexually transmitted infections (STIs), accompanied by a lack of trust in test results. This behavior is driven by an ongoing, obsessive monitoring of presumed venereal symptoms, either localized to the external genitalia or presenting at a systemic level.

The marked predominance of male subjects among individuals exhibiting such behaviors can be partly attributed to the higher frequency of occasional sexual encounters with sex workers within this group. Additionally, male individuals are more likely to directly observe presumed alterations or symptomatic manifestations of pathological conditions on their own genitalia.

The Authors of these studies underline how, in such cases, a dismissive approach on the part of the clinician in excluding any potential infectious risk, could result ineffective in overcoming the obsessive approach of the patient, no matter how clear the absence of risk factors is.

These studies also highlight a high incidence, in the group of patients analyzed, of anxiety and depression disorders associated with a wrong perception of potential infectious risks. This misperception is often linked to arbitrary interpretations of STD-related contents found online.

In a study reported online on Cambridge University Press in 2020 [9], the phenomenon of HIV worried well was analyzed in the European context by a group of professionals working within a clinical structure dedicated to psychiatry and mental health in the city of Porto, Portugal.

What emerges from the study highlights how the management of HIV-related WW people represents an extremely complex aspect from a psychiatric point of view, since these subjects, despite solid evidence regarding the absence of an infection and/or of concrete risk factors, continue to access healthcare facilities to carry out tests and other health checks, fearing that healthcare personnel may have made diagnosis errors.

Different kinds of painful and traumatic experiences are often found in the past history of these individuals: addictions, serious relational and family problems, psychiatric precedents, alongside with a poor ability to read and interpret informative materials on HIV and AIDS found online.

It should be emphasized that the incidence of various types of psychiatric disorders was found to be very high.

It is clear, however, that the phenomenon has assumed a global dimension over time, albeit with some specific traits in the different territorial, health and cultural contexts in which it is observed.

In this framework, it is noteworthy that in the Canadian province of Ontario, the Hassle Free Clinic – a network providing free medical and counselling services for sexually transmitted infections (STIs) and a key access point for anonymous HIV testing – found it necessary to implement specific counselling guidelines. These guidelines are directed at counsellors, healthcare providers conducting the tests, and educators, with the aim of facilitating the management of interactions with users exhibiting high levels of HIV-related anxiety despite having minimal or no actual risk exposure [10].

An additional aspect that warrants attention is the concern over the potential impact of an HIV-positive diagnosis on individuals’ relational and social lives. In some cases, this concern appears to outweigh fears related to the physical health implications of the diagnosis, underscoring the enduring influence of HIV-related stigma, rooted in decades of stigma-laden media discourse.

In this connexion, it is useful to investigate whether the COVID-19 pandemic may have further accentuated anxious states and obsessive behaviors such as those described in the abovementioned studies, and whether the communication campaigns on infectious risks, the restrictions on people’s freedom of movement and, in general, all the measures adopted to restrict the contagion, may have aggravated these conditions, where pre-existing, and/or expanded the number of people with a similar profile, thus favoring the emergence of latent frailties.

The extant scientific literature indicates that social isolation, pandemic-related socio-economic challenges, uncertainties regarding transmission pathways, and fear of contagion have contributed to a marked increase in health-related anxiety disorders. In this context, the extensive experience accumulated over decades in addressing HIV infection and its associated stigma constitutes a valuable precedent for the design and implementation of targeted interventions. These interventions should aim to facilitate the referral of individuals to counseling and mental health services, thereby enabling effective mitigation of phenomena such as health-related anxiety and suicidal ideation [11].

Restricting the analysis to the European context (EU and EEA countries), an assessment of the consequences of COVID-19 on mental health highlighting a stronger impact of the pandemic on the population, in terms of increase in the incidence of anxiety and depressive symptoms, is contained in the document titled “Public health and social measures for health emergencies and pandemics in the EU/EEA: recommendations for strengthening preparedness planning”, published by the European Center for Disease Prevention and Control (ECDC) in March 2024 [12], in which it is stated: “…In addition, the pandemic impacted on the mental health of the population in most European countries, reflected by increases in reported anxiety and depressive disorders...”.

Limitations

The limitations of this study were already taken into consideration in designing the statistical analysis.

They can be summed up as follows:

  • telephone calls are anonymous, therefore users cannot be easily identified and followed over time, although the service operators, working as a team, are in most cases able to recognize the behavioral patterns and distinctive traits of most WW users;
  • all the information collected during the counselling interview is self-reported by the user and there is no possibility of carrying out any objective checks or direct observations;
  • it is not always possible to recognize users who call repeatedly, as the information they provide regarding their age, geographic origin, etc., can be modified by them over time. Nevertheless, teamwork and the recurrence of behavioural patterns greatly assist operators in identifying the origin of the WW calls;
  • the telephone interview only allows the detection of the verbal and paraverbal elements of the communication, while the relevant non-verbal aspects in the relationship between the expert and the user are missing.

CONCLUSIONS

A significant finding emerging from the analysis of telephone calls made by WW users to the AIDS and STIs Helpline is the widespread lack of adequate cognitive and interpretive tools necessary to effectively filter, comprehend, and contextualize the extensive amount of online information available on STIs.

In this regard, it could be useful to interpret the phenomenon under study by also placing it in a broader framework. For many years now, the scientific community has been wondering about the extent of the effects produced by the inability of some individuals to recognize their incompetence with respect to certain subjects and the consequent construction of false beliefs in that field.

The effect of this unawareness is twofold: on the one hand, these people often reach erroneous conclusions, on the other hand, their unconscious incompetence deprives them of the metacognitive ability to recognize their own errors [13].

This lack of cognitive tools is actually found in a much larger number of users than that represented by the WW sample, and it might constitute an important indicator of a substantial absence of structured sexual education programs in school curricula.

As a matter of fact, though it is undeniable that the discomfort expressed by WW people often finds its most direct cause in traumas and problematic personal experiences which heavily influence the way in which sexuality is perceived and experienced by the individual, it can be assumed that improving quality education through the integration of sexual education and prevention of STIs programs into compulsory school curricula, would represent a valuable action to enhance good health and well-being and combat, or at least mitigate, the misinformation and the fallacious interpretation of scientific contents found online, of which the WW phenomenon represents a problematic fallout.

Nonetheless, it is crucial to point out that AIDS and STIs Helpline operators, upon identifying a call from a WW user, consistently endeavor to prompt the individual to reflect on the potential benefits of confronting their fears and cognitive distortions through engagement in a psychotherapeutic process.

Finally, as previously noted, the cultural perception of HIV infection – far more so than other sexually transmitted infections – has been deeply shaped over the years by media communication, as well as by cinema, literature, and social media. This layered cultural framing has significantly hindered efforts to combat the persistent stigma associated with the virus. Concurrently, the heightened attention and fear surrounding HIV complicate the ability of healthcare professionals to effectively communicate preventive information regarding other STIs [14].

Other Information

Funding

The study was conducted with the resources of the Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione – UO RCF – and did not receive any third-party funding.

Availability of data and material

The collection of the relevant data gathered during the counselling interventions is based on a data-entry software, through which information relating to both the user calling and to the topic areas covered within the counselling intervention is anonymously collected and stored.

Code availability (software application or custom code)

The descriptive analysis of the aggregate data collected during the telephone interventions was carried out using the Access 365 software.

Authors’ contributions

All Authors contributed significantly to the study design and interpretation of results and critically reviewed and approved the final version of the manuscript.

Conflict of interest statement

No potential conflict of interest was reported by the Authors.

Address for correspondence: Matteo Schwarz, Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione – UO RCF – Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy. E-mail: matteo.schwarz@iss.it

Figures and tables

Figure 1. Gender analysis of calls by worried well (WW).

General calls without worried well Calls of worried well
n=53,068 n=4,703
Variables p-value method
N questions (means) 192,667 (average of questions per call=3.9) 16,401 (average of questions per call=3.5)
Gender 0.000 chi square
Male 45,104 85.0% 3,794 80.7%
Female 7,953 15.0% 909 19.3%
Not binary 11 0.0% 0 0.0%
Age
Means age 35.8 40.9 0.0001 t-test indipendent samples
Median age 35 41
IQR (28-42) (33-47)
HIV in the past 0.000 chi square
No 20,343 38.3% 576 12.2%
Yes 24,726 46.6% 1,595 33.9%
Not indicated 7,999 15.1% 2,532 53.8%
Questions with Risk factor for STI/HIV 0.000 chi square
No 52,131 76.9% 2,745 96.3%
Yes 15,672 23.1% 105 3.7%
Type of question 0.000 chi square
Ways of transmission 67,803 35.2% 2,850 17.4%
Information on tests 56,632 29.4% 2,613 15.9%
Psyco-social aspects 22,568 11.7% 2,609 15.9%
Misinformation 14,703 7.6% 4,180 25.5%
Contagiousness and survival of pathogens 10,487 5.4% 2,806 17.1%
Prevention 7,749 4.0% 219 1.3%
Symptoms 5,723 3.0% 281 1.7%
Therapy and research 2,937 1.5% 136 0.8%
Other 4,065 2.1% 707 4.3%
Total 192,667 16,401
IQR: interquartile range; STI: sexually transmitted diseases.
Table 1. Table comparing call characteristics between worried well and general callers (without worried well)
Variables Years 2018-2019 Years 2020-2021 Years 2022-2023 Total
Geographical area N % N % N % N %
North 774 38.3% 501 33.2% 417 35.6% 1,692 36.0%
Centre 530 26.2% 359 23.8% 324 27.7% 1,213 25.8%
South 562 27.8% 529 35.1% 369 31.5% 1,460 31.0%
Islands 155 7.7% 118 7.8% 61 5.2% 334 7.1%
Not indicated 2 0.1% 1 0.1% 1 0.1% 4 0.1%
Total 2,021 100.0% 1,507 100.0% 1,171 100.0% 4,703 100.0%
Gender N % N % N % N %
Men 1,618 80.0% 1,191 79.0% 985 84.0% 3,794 80.7%
Women 405 20.0% 317 21.0% 187 16.0% 909 19.3%
Not binary 0 0.0% 0 0.0% 0 0.0% 0 0.0%
Total 2,023 100.0% 1,508 100.0% 1,172 100.0% 4,703 100.0%
Age N % N % N % N %
From 10 to 19 9 0.4% 6 0.4% 1 0.1% 16 0.3%
From 20 to 29 279 13.8% 213 14.1% 151 12.9% 643 13.7%
From 30 to 39 691 34.2% 424 28.1% 333 28.4% 1,448 30.8%
From 40 to 49 740 36.6% 573 38.0% 362 30.9% 1,675 35.6%
Above 50 303 15.0% 291 19.3% 318 27.1% 912 19.4%
Not indicated 1 0.0% 1 0.1% 7 0.6% 9 0.2%
Total 2,023 100.0% 1,508 100.0% 1,172 100.0% 4,703 100.0%
Call frequency N % N % N % N %
More than 15 calls 702 34.7% 868 57.6% 606 51.7% 2,176 46.3%
More than 5 calls 995 49.2% 487 32.3% 374 31.9% 1,856 39.5%
From 2 to 5 calls 326 16.1% 153 10.1% 192 16.4% 671 14.3%
Total 2,023 100.0% 1,508 100.0% 1,172 100.0% 4,703 100.0%
Previous HIV test N % N % N % N %
No 282 13.9% 208 13.8% 86 7.3% 576 12.2%
Not indicated 1,090 53.9% 809 53.6% 633 54.0% 2,532 53.8%
Yes, more than one 463 22.9% 357 23.7% 345 29.4% 1,165 24.8%
Yes 188 9.3% 134 8.9% 108 9.2% 430 9.1%
Total 2,023 100.0% 1,508 100.0% 1,172 100.0% 4,703 100.0%
Questions’ topic N % N % N % N %
Misinformation 1,725 26.0% 1,380 25.0% 1,076 25.3% 4,181 25.5%
Total 6,632 100.0% 5,524 100.0% 4,245 100.0% 16,401 100.0%
Table 2. Comparison between the numbers relating to calls from WW users in the three two-year periods of study

References

  1. Miller D, Acton T, Hedge B. The worried well: their identification and management. J R Coll Physicians Lond. 1988;22(3):158-65.
  2. Mahajan B, Shishak M. An approach to venerophobia in males. Indian J Sex Transm Dis AIDS. 2017;38:103-6.
  3. Chowdhry S, Jaiswal P, Souza P, Dhali T. Venerophobia – Sexually transmitted disease. J Emerg Dis Virol. 2018;4(1).
  4. Shekhar K, Adhikary M, Karn D. Clinical scenario of venerophobia in patients presenting in outpatient department. J Nepal Health Res Counc. 2020;18(3):483-7.
  5. Hafi B, Uvais N, Latheef E, Razmi M, Afra T, Aysha S. Venereophobia – a cognitive deception? Case reports with literature review. Our Dermatol Online. 2020;11(e):e138.1-e138.5.
  6. Spence D. Bad medicine: the worried hell. Br J Gen Pract. 2016;66(651).
  7. Mevissen F, Eiling E, Bos A, Tempert B, Mientjes M, Schaalma H. Evaluation of the Dutch AIDS STI information helpline: differential outcomes of telephone versus online counseling. Patient Educ Couns. 2012;88(2):218-23.
  8. Luzi A, Colucci A, Gallo P, De Mei B, Mastrobattista L, De Santis M. The communicative-relational operating model of the Italian National Institute of Health for an effective telephone intervention in public health, structured on basic counselling skills. Ann Ig. 2023;35(4):379-402.
  9. Marinho M, Covelo V, Marques J, Braganca M. HIV/AIDS “worried well” – When the “virus” leads to a significant illness, even in its absence. Eur Psychiatry. 2017;41:S170-S237.
  10. Counselling guidelines – Clients with high HIV anxiety and no/low risk. Hassle Free Clinic; 2021.
  11. Kini G, Karkal R, Bhargava M. All’s not well with the “worried well”: understanding health anxiety due to COVID-19. J Prev Med Hyg. 2020;61(3):E321-3.
  12. Public health and social measures for health emergencies and pandemics in the EU/EEA: recommendations for strengthening preparedness planning. Stockholm: ECDC; 2024.
  13. Kruger J, Dunning J. Unskilled and unaware of it: how difficulties in recognizing one’s own incompetence lead to inflated self-assessments. J Pers Soc Psychol. 1999;77(6):1121-34.
  14. Vallorani N. Corpi estranei. Linguaggi medici e artistici nella rappresentazione dell’AIDS. Studi Culturali, Rivista Quadrimestrale. 2010;2:261-78.

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Authors

Matteo Schwarz - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Pietro Gallo - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Anna Colucci - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Emanuele Fanales Belasio - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Rudi Valli - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Rosa Dalla Torre - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

Camilla Gallo - Media, Comunicazione Digitale e Giornalismo, Sapienza Università di Roma, Rome, Italy

Anna D'Agostini - Unità Operativa Ricerca Psico-Socio-Comportamentale, Comunicazione, Formazione, Dipartimento Malattie Infettive, Istituto Superiore di Sanità, Rome, Italy

How to Cite
Schwarz, M., Gallo, P., Colucci, A., Fanales Belasio, E., Valli, R., Dalla Torre, R., Gallo, C., & D'Agostini, A. (2025). Examining the "worried well" phenomenon: insights from Italy’s AIDS and STIs Helpline. Annali dell’Istituto Superiore Di Sanità, 61(4), 293–300. https://doi.org/10.4415/ANN_25_04_08
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