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Building AI-ready health systems: the AULSS6 (Padua, Italy) local health authority artificial intelligence implementation strategy

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Abstract

Objectives. To present the strategy developed by the Local Health Authority AULSS6, Padua Province, Italy, for implementing artificial intelligence (AI) in healthcare systems.
Methods. Between December 2024 and December 2025, a series of structured meetings of a multidisciplinary Steering Committee were conducted. Ideas, priorities and initiatives were systematically collected, categorized, and refined through consensus.
Results. The strategy produced several outcomes: an AI ethics and readiness checklist ensuring compliance with the EU AI Act, GDPR, (EU General Data Protection Regulation) and cybersecurity requirements; multi-level education programs for staff; systematic
technology evaluation guidelines and HTA (Health Technology Assessment) evaluation studies planning; active participation in projects on AI for public health and clinical outcomes prediction and resource optimization; communication strategies designed to enhance transparency and trust. Collectively, these initiatives enabled AULSS6 to build institutional capacity for responsible AI adoption at the local level.
Conclusions. AULSS6 shows that local health authorities can lead responsible AI implementation in healthcare. Its multidimensional approach close to the population offers a replicable, scalable model for health systems across Italy and Europe, advancing digital
transformation through a bottom-up strategy close to the communities served.

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Authors

Carlo Giordani - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Marcello Di Pumpo - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Fabio Senarigo - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Chiara Zambon - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Maddalena Valli - Grimaldi Alliance, Padua, Italy

Luca Gino Sbrogiò - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Nadia Milano - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Giulia Gusella - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Tullio Zampieri - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Francesco Allegro - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Chiara Bovo - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Laura Biasi - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Elena Debora Toffanello - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Pietro Viena - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Angela Vinelli - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Susanna Visonà - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Michela Barbiero - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

Paolo Fortuna - Azienda ULSS6 Euganea, Regione del Veneto, Padua, Italy

How to Cite
Giordani, C., Di Pumpo, M., Senarigo, F., Zambon, C., Valli, M., Sbrogiò, L. G., Milano, N., Gusella, G., Zampieri, T., Allegro, F., Bovo, C., Biasi, L., Toffanello, E. D., Viena, P., Vinelli, A., Visonà, S., Barbiero, M., & Fortuna, P. (2026). Building AI-ready health systems: the AULSS6 (Padua, Italy) local health authority artificial intelligence implementation strategy. Annali dell’Istituto Superiore Di Sanità, 62(1), 87–90. https://doi.org/10.4415/ANN_26_01_11
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