A combination of infrared spectroscopy and morphological analysis allows successfully identifying rare crystals and atypical urinary stones
Authors
Aniello Primiano, Silvia Persichilli, Pietro Manuel Ferraro, Angelo Minucci, Giovanni Gambaro, Andrea Urbani, Jacopo Gervasoni
Abstract
Background:
The combination of infrared spectroscopy and morphological analysis significantly improves the urinary stone analysis.
In addition to common urinary stones, it is not unusual to encounter spurious or factitious stones that, if not appropriately identified, can lead to errors in the diagnosis. In this study we shows the importance of Infrared spectroscopy and the morphological analysis, for determining the presence of drugs crystals or atypical components in the calculi.
Methods: among 1.041 urinary stones analyzed by morphocostitutional analysis the rare stones were also analyzed by chemical spot test analysis.
Results: Among 1.041 calculi analyzed, 1.018 had a known composition, 23 samples were stones with rare composition or fake urinary stones.
Conclusions: FT-IR, allows to identify, theoretically, any substance, including drug-containing calculi or calculi with unusual composition and identify false stones. This is mandatory to treat patients affected by urolithiasis with a personalized clinical approach.
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