Cancer incidence and congenital anomalies evaluation in the contaminated sites of Sesto San Giovanni – the SENTIERI Project

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Abstract

The Italian Institute for Environmental Protection and Research defines National Priority Contaminated Sites (NPCSs) as land where hazardous substances are likely to pose a risk to human health. SENTIERI was the first national project evaluating the health status of residents in NPCSs. We have extended, for the site of Sesto San Giovanni, the evaluation to cancer incidence and congenital anomalies (CAs). We have found an overall protective effect of living in the NPCS for overall cancer incidence in all ages and no association in paediatric, adolescent and young adults’ population. We have found an excess risk for bladder cancer, leukaemia, lymphoid leukaemia and chronic lymphocytic leukaemia in men and for lung and breast cancer in women. For the paediatric and adolescent population, we have found an excess in embryonic tumours. Total CAs were not different from expected, while we have found excesses regarding congenital ear, face and neck, digestive system and chromosomal defects.
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Authors

Rossella Murtas - Unit of Epidemiology, Agency for Health Protection (ATS) of Milan https://orcid.org/0000-0002-8989-7605

Anita Andreano - Unit of Epidemiology, Agency for Health Protection (ATS) of Milan

Maria Teresa Greco - Unit of Epidemiology, Agency for Health Protection (ATS) of Milan

Sara Tunesi - Unit of Epidemiology, Agency for Health Protection (ATS) of Milan

Antonio Giampiero Russo - Unit of Epidemiology, Agency for Health Protection (ATS) of Milan

How to Cite
Murtas, R., Andreano, A., Greco, M. T., Tunesi, S., & Russo, A. G. (2019). Cancer incidence and congenital anomalies evaluation in the contaminated sites of Sesto San Giovanni – the SENTIERI Project. Annali dell’Istituto Superiore Di Sanità, 55(4), 345-350. Retrieved from https://annali.iss.it/index.php/anna/article/view/828
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