Vol. 55 No. 4 (2019)
Commentary
Original Articles
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Effects of short-term aerobic exercise in a mouse model of Niemann-Pick type C Disease on synaptic and muscle plasticity
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Ketamine abusers referring to Emergency Departments in Northern Italy: a cross- sectional study
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Cancer incidence and congenital anomalies evaluation in the contaminated sites of Sesto San Giovanni – the SENTIERI Project
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Blood transfusions and adverse acute events: a retrospective study from 214 transfusion-dependent pediatric patients comparing transfused blood components by apheresis or by whole blood
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A web-based tumor registration system for a regional Canine Cancer Registry in Umbria, central Italy
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The way to move beyond the numbers: the lesson learnt from the Italian Obstetric Surveillance System
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Understanding mechanisms of cancer initiation and development supports the need for an implementation of primary and secondary cancer prevention
Brief note
Monographic Section
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The 3R principle: 60 years taken well. Preface
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The usefulness of integrated strategy approaches in replacing animal experimentation
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Considering the microbiota to achieve reduction in the numbers of animals used in scientific studies
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Refinement techniques in non-human primate neuroscientific research
Book Reviews, Notes and Comments
Publications from International Organizations on Public Health
Acknowledgement to Referees
Information
Announcements
The Annali dell'Istituto Superiore di Sanità Impact Factor
We are proud to announce that the Impact Factor for the journal Annali dell'Istituto Superiore di Sanità has grown from 1.663 in 2020 to 2.210 in 2021.
Read moreCOVID-19 and impact on peer review
As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers will have difficulty in meeting the deadlines associated with our peer review process.
Read moreINTERVIEW WITH PAOLO NICHELLI
by Enrico Alleva